Maternal smoking and orofacial clefts.

  title={Maternal smoking and orofacial clefts.},
  author={Karin K{\"a}ll{\'e}n},
  journal={The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association},
  volume={34 1},
  • Karin Källén
  • Published 1997 in
    The Cleft palate-craniofacial journal : official…
To investigate a possible association between maternal smoking during pregnancy and oral clefts, a study was conducted using Swedish health registries. Infants with oral clefts (N = 1834) were selected among 1,002,742 infants born between 1983 and 1992 with known smoking exposure in early pregnancy. Confounders such as maternal age and parity were controlled for by using the Mantel-Haenszel technique. A statistically significant association with maternal smoking was found. The odds ratio (OR… CONTINUE READING

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