Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk.

@article{Jenkins2014MaternalSX,
  title={Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk.},
  author={Mary M Jenkins and Jennita Reefhuis and Margaret L. Gallagher and Jennifer Gladys Mulle and Thomas J. Hoffmann and Deborah A. Koontz and Cynthia Sturchio and Sonja A Rasmussen and John S. Witte and Patricia Richter and Margaret A. Honein},
  journal={American journal of medical genetics. Part A},
  year={2014},
  volume={164A 6},
  pages={1454-63}
}
Maternal smoking during pregnancy is one proposed risk factor for gastroschisis, but reported associations have been modest, suggesting that differences in genetic susceptibility might play a role. We included 108 non-Hispanic white and 62 Hispanic families who had infants with gastroschisis, and 1,147 non-Hispanic white and 337 Hispanic families who had liveborn infants with no major structural birth defects (controls) in these analyses. DNA was extracted from buccal cells collected from… CONTINUE READING