Maternal serum cell-free fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18

@article{Wataganara2002MaternalSC,
  title={Maternal serum cell-free fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18},
  author={Tuangsit Wataganara and Erik S. Leshane and Antonio Farina and Geralyn M Messerlian and Thomas Lee and Jacob A. Canick and Diana W. Bianchi},
  journal={Human Genetics},
  year={2002},
  volume={112},
  pages={204-208}
}
Abstract. Cell-free fetal DNA in the maternal circulation is a potential noninvasive marker for fetal aneuploidies. In previous studies with Y DNA as a fetal-specific marker, levels of circulating fetal DNA were shown to be elevated in women carrying trisomy 21 fetuses. The goal of this study was to determine whether cell-free fetal DNA levels in the serum of pregnant women carrying fetuses with trisomies 13 or 18 are also elevated. Archived maternal serum samples from five cases of male… 
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