Maternal serum cell-free fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18

@article{Wataganara2002MaternalSC,
  title={Maternal serum cell-free fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18},
  author={T. Wataganara and E. Leshane and A. Fari{\~n}a and G. Messerlian and T. Lee and J. Canick and D. Bianchi},
  journal={Human Genetics},
  year={2002},
  volume={112},
  pages={204-208}
}
  • T. Wataganara, E. Leshane, +4 authors D. Bianchi
  • Published 2002
  • Biology, Medicine
  • Human Genetics
  • Abstract. Cell-free fetal DNA in the maternal circulation is a potential noninvasive marker for fetal aneuploidies. In previous studies with Y DNA as a fetal-specific marker, levels of circulating fetal DNA were shown to be elevated in women carrying trisomy 21 fetuses. The goal of this study was to determine whether cell-free fetal DNA levels in the serum of pregnant women carrying fetuses with trisomies 13 or 18 are also elevated. Archived maternal serum samples from five cases of male… CONTINUE READING
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