Maternal serum alpha-fetoprotein levels in pregnancies complicated by diabetes: implications for screening programs.

@article{Martin1990MaternalSA,
  title={Maternal serum alpha-fetoprotein levels in pregnancies complicated by diabetes: implications for screening programs.},
  author={Alice O. Martin and Lorcan Dempsey and J P Minogue and Ken Liu and Jerry Keller and Ritsu Tamura and Norbert Freinkel},
  journal={American journal of obstetrics and gynecology},
  year={1990},
  volume={163 4 Pt 1},
  pages={1209-16}
}
Maternal serum alpha-fetoprotein may be reduced in diabetic pregnancies, but the association with elevated glycosylated hemoglobin has been controversial. We tested the hypothesis that reductions in maternal serum alpha-fetoprotein may reflect the same phenomena that can also impair normal rates of embryo growth in the presence of poorly compensated maternal diabetes. If so, associations would be expected among maternal serum alpha-fetoprotein, embryo rates of growth, and levels of glycosylated… CONTINUE READING