Maternal separation alters acquisition of ethanol intake in male ethanol-preferring AA rats.

BACKGROUND Prolonged daily maternal separation can increase the risk for developing substance abuse, whereas brief maternal separation has been reported to induce positive behavioral effects, decrease voluntary ethanol intake and induce long-lasting changes in brain opioid peptides. The ethanol-preferring AA (Alko, Alcohol) rats have altered basal levels of… CONTINUE READING