Maternal plasma soluble TRAIL is decreased in preeclampsia.

  title={Maternal plasma soluble TRAIL is decreased in preeclampsia.},
  author={Piya Chaemsaithong and Tinnakorn Chaiworapongsa and Roberto Romero and Steven J Korzeniewski and Tamara Stampalija and N{\'a}ndor G{\'a}bor Than and Zhong Dong and Jezid Miranda and Lami Yeo and Sonia S. Hassan},
  journal={The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians},
  volume={27 3},
OBJECTIVE Preeclampsia (PE) is characterized by systemic intravascular inflammation. Women who develop PE are at an increased risk for cardiovascular disease in later life. Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) has anti-atherosclerotic effects in endothelial cells and can mediate neutrophil apoptosis. Low soluble TRAIL (sTRAIL) and high C-reactive protein (CRP) concentrations are associated with an increased risk of future cardiovascular disease in non-pregnant… CONTINUE READING