Maternal plasma cytokines in early- and mid-gestation of normal human pregnancy and their association with maternal factors.

@article{Curry2008MaternalPC,
  title={Maternal plasma cytokines in early- and mid-gestation of normal human pregnancy and their association with maternal factors.},
  author={Allison Elizabeth Curry and Ida Vogel and Kristin Skogstrand and Carolyn D Drews and Diana Elizabeth Schendel and W Dana Flanders and David Michael Hougaard and Poul Thorsen},
  journal={Journal of reproductive immunology},
  year={2008},
  volume={77 2},
  pages={152-60}
}
Few studies have assessed longitudinal changes in circulating cytokine levels during normal pregnancy. We have examined the natural history of maternal plasma cytokines from early- to mid-pregnancy in a large, longitudinal cohort. Multiplex flow cytometry was used to measure interleukin (IL)-2, IL-6, IL-12, tumor necrosis factor (TNF)-alpha, interferon (IFN)-gamma and granulocyte-macrophage colony-stimulating factor (GM-CSF) in early- (median [IQR]: 8.5 weeks [7.1, 10.0]) and mid-pregnancy (25… CONTINUE READING

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