Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.

@article{Jahreis2017MaternalPE,
  title={Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.},
  author={Susanne Jahreis and Saskia Trump and Mario Bauer and Tobias Bauer and Loreen Th{\"u}rmann and Ralph Feltens and Qi Wang and Lei Gu and Konrad Gr{\"u}tzmann and Stefan W. Roeder and Marco Averbeck and Dieter Weichenhan and Christoph Plass and Ulrich Sack and Michael Borte and Virginie Dubourg and Gerrit Sch{\"u}{\"u}rmann and Jan C. Simon and Martin von Bergen and J{\"o}rg Hackerm{\"u}ller and Roland Eils and Irina Lehmann and Tobias Polte},
  journal={The Journal of allergy and clinical immunology},
  year={2017},
  volume={141 2},
  pages={
          741-753
        }
}
BACKGROUND Prenatal and early postnatal exposures to environmental factors are considered responsible for the increasing prevalence of allergic diseases. Although there is some evidence for allergy-promoting effects in children because of exposure to plasticizers, such as phthalates, findings of previous studies are inconsistent and lack mechanistic information. OBJECTIVE We investigated the effect of maternal phthalate exposure on asthma development in subsequent generations and their… CONTINUE READING
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