Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring.

@article{Tozuka2010MaternalOI,
  title={Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring.},
  author={Yusuke Tozuka and Mami Kumon and Etsuko Wada and Masafumi Onodera and Hideki Mochizuki and Keiji Wada},
  journal={Neurochemistry international},
  year={2010},
  volume={57 3},
  pages={235-47}
}
Maternal obesity may affect the child's long-term development and health, increasing the risk of diabetes and metabolic syndrome. In addition to the metabolic and endocrine systems, recent reports have indicated that maternal obesity also modulates neural circuit formation in the offspring. However, this not yet been fully investigated. Here, we examined the effect of diet-induced maternal obesity on hippocampal development and function in the mouse offspring. Adult female mice were fed either… CONTINUE READING
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