Maternal multivitamin use and orofacial clefts in offspring.

  title={Maternal multivitamin use and orofacial clefts in offspring.},
  author={P R Itikala and M. L. Watkins and Joseph Mulinare and Cynthia A. Moore and Yecai Liu},
  volume={63 2},
BACKGROUND Cleft lip with or without cleft palate (CLP) and cleft palate alone (CP) affect approximately 1 in 1000 infants and 1 in 2,500 infants, respectively. Studies of the relation between orofacial clefts and multivitamins or folic acid have been inconsistent. METHODS We used data from a population-based case-control study involving 309 nonsyndromic cleft-affected births (222 with CLP, 87 with CP) and 3,029 control births from 1968 to 1980 to evaluate the relation between regular… CONTINUE READING
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