Maternal malnutrition programs pancreatic islet mitochondrial dysfunction in the adult offspring.

@article{Theys2011MaternalMP,
  title={Maternal malnutrition programs pancreatic islet mitochondrial dysfunction in the adult offspring.},
  author={Nicolas Theys and Marie-Th{\'e}r{\`e}se Ahn and Thomas Bouckenooghe and Brigitte M Reusens and Claude A Remacle},
  journal={The Journal of nutritional biochemistry},
  year={2011},
  volume={22 10},
  pages={985-94}
}
Accumulating evidence has shown that maternal malnutrition increases the risk of metabolic disease in the progeny. We previously reported that prenatal exposure to a low-protein diet (LP) leads to mitochondrial dysfunction in pancreatic islets from adult rodent offspring that could relate physiological and cellular alterations due to early diet. We aim to determine whether mitochondrial dysfunction could be a common consequence of prenatal nutritional unbalances. Pregnant Wistar rats received… CONTINUE READING

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