Maternal insulin treatment improves pre-implantation embryo development in diabetic rats


Pre-implantation embryos were recovered from control, diabetic and insulin-treated diabetic rats on day 5 of pregnancy. Compared to control animals, diabetic rats had a 20 % reduction in the number of embryos per rat and blastocysts recovered from diabetic rats showed a 19 % decrease in total cell number. The cellular decrease observed in blastocysts was… (More)
DOI: 10.1007/BF02342434


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