Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT₂A and mGlu₂ receptors in the adult offspring.

@article{Moreno2011MaternalIV,
  title={Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT₂A and mGlu₂ receptors in the adult offspring.},
  author={Jose Luis Moreno and Mitsumasa Kurita and Terrell Holloway and Javier L{\'o}pez and Richard Cadagan and Luis Mart{\'i}nez-Sobrido and Adolfo Garc{\'i}a-Sastre and Javier Gonz{\'a}lez-Maeso},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 5},
  pages={1863-72}
}
Epidemiological studies indicate that maternal influenza viral infection increases the risk for schizophrenia in the adult offspring. The serotonin and glutamate systems are suspected in the etiology of schizophrenia, as well as in the mechanism of action of antipsychotic drugs. The effects of hallucinogens, such as psilocybin and mescaline, require the serotonin 5-HT(2A) receptor, and induce schizophrenia-like psychosis in humans. In addition, metabotropic glutamate receptor mGlu(2/3) agonists… CONTINUE READING

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