Maternal immunoglobulin G avidity as a diagnostic tool to identify pregnant women at risk of congenital cytomegalovirus infection.


BACKGROUND The immunoglobulin (Ig) G avidity index (AI) is useful to detect primary cytomegalovirus (CMV) infection. However, because IgG matures with time, this index is not useful to detect a primary infection, unless measured at an appropriate time. OBJECTIVES We aimed to clarify the difference between using IgG AI and IgM positivity according to the… (More)
DOI: 10.1016/j.jiac.2016.12.001