Maternal high-fat diet programs rat offspring hypertension and activates the adipose renin-angiotensin system.

@article{Guberman2013MaternalHD,
  title={Maternal high-fat diet programs rat offspring hypertension and activates the adipose renin-angiotensin system.},
  author={Cristiane Guberman and Juanita K. Jellyman and Guang Han and Michael G. Ross and Mina Desai},
  journal={American journal of obstetrics and gynecology},
  year={2013},
  volume={209 3},
  pages={262.e1-8}
}
OBJECTIVE A maternal high-fat diet creates an increased risk of offspring obesity and systemic hypertension. Although the renal renin-angiotensin system (RAS) is known to regulate blood pressure, it is now recognized that the RAS is also activated in adipose tissue during obesity. We hypothesized that programmed offspring hypertension is associated with the… CONTINUE READING