Maternal glucocorticoid deficit affects hypothalamic–pituitary–adrenal function and behavior of rat offspring

@article{Wilcoxon2007MaternalGD,
  title={Maternal glucocorticoid deficit affects hypothalamic–pituitary–adrenal function and behavior of rat offspring},
  author={Jennifer Slone Wilcoxon and Eva E Redei},
  journal={Hormones and Behavior},
  year={2007},
  volume={51},
  pages={321-327}
}
Detrimental consequences of prenatal stress include increased hypothalamic-pituitary-adrenal (HPA) function, anxiety and depression-like behavior in adult offspring. To identify the role of maternal corticosterone milieu in the fetal programming of adult function, we measured these same behavioral and hormonal endpoints after maternal adrenalectomy (ADX) and replacement with normal or moderately high levels of corticosterone (CORT). Adult male and female offspring exhibited differing HPA… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

Similar Papers

Loading similar papers…