Maternal fenvalerate exposure during pregnancy persistently impairs testicular development and spermatogenesis in male offspring.

@article{Zhang2010MaternalFE,
  title={Maternal fenvalerate exposure during pregnancy persistently impairs testicular development and spermatogenesis in male offspring.},
  author={Heng Zhang and Hua Wang and Yan-Li Ji and Ying Zhang and Tao Yu and Huan Ning and Cheng Zhang and Xian-feng Zhao and Qunjing Wang and Ping Liu and De-Xiang Xu},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2010},
  volume={48 5},
  pages={1160-9}
}
Fenvalerate, a widely used pyrethroid insecticide, has been associated with poor semen quality. As yet, little is known about the effects of prenatal fenvalerate exposure on testicular development. The present study investigated the effects of prenatal fenvalerate exposure on testicular development and spermatogenesis. The pregnant mice were administered fenvalerate (30 mg/kg) by gavage daily from gestational day (gd) 13 to gd 18. The weights of testes and epididymides were significantly… CONTINUE READING