Maternal-effect Floped gene is essential for the derivation of embryonic stem cells in mice.

Abstract

Floped (official name Ooep) is specifically and abundantly expressed in mouse oocytes and embryonic stem cells (ESCs). Depletion of Floped from oocytes leads to early embryonic arrest at the 2-cell stage. Although crucial in cleavage stage development, its roles in early embryos as well as in ESCs remain completely unknown. Here, we compared the efficiency… (More)

Topics

Cite this paper

@article{Zhao2013MaternaleffectFG, title={Maternal-effect Floped gene is essential for the derivation of embryonic stem cells in mice.}, author={Bo Zhao and Yi-Xian Cun and Xie-chao He and Ping Zheng}, journal={Dong wu xue yan jiu = Zoological research}, year={2013}, volume={34 E3}, pages={E82-6} }