Maternal dietary chromium restriction programs muscle development and function in the rat offspring

@article{Padmavathi2010MaternalDC,
  title={Maternal dietary chromium restriction programs muscle development and function in the rat offspring},
  author={Inagadapa J.N. Padmavathi and Kalashikam Rajender Rao and Lagishetty Venu and Ayesha Ismail and Manchala Raghunath},
  journal={Experimental Biology and Medicine},
  year={2010},
  volume={235},
  pages={349 - 355}
}
Intrauterine growth retardation programs the fetus to manipulated metabolic changes that lead to adult diseases. Considering that chromium (Cr) supplements influence lean body mass (LBM) in both humans and experimental animals, we have studied the effect of maternal Cr restriction on muscle development and function in the rat offspring. Female weanling Wistar/NIN rats received, for 12 weeks, a control or 65% Cr-restricted diet ad libitum and mated with control males. While control mothers… 

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References

SHOWING 1-10 OF 48 REFERENCES
Maternal and perinatal magnesium restriction predisposes rat pups to insulin resistance and glucose intolerance.
TLDR
Maternal magnesium restriction irreversibly increases body fat and induces insulin resistance in pups by 6 mo of age, whereas additional perinatal Mg deficiency impairs glucose tolerance.
Does maternal dietary mineral restriction per se predispose the offspring to insulin resistance?
TLDR
Maternal MR per se resulted in an increase in body fat and in plasma triacylglycerol concentrations in the offspring, however, no discernable effect on insulin sensitivity over the first 180 days of life.
Prenatal and perinatal zinc restriction: effects on body composition, glucose tolerance and insulin response in rat offspring
TLDR
Chronic maternal zinc restriction altered the body composition and impaired the glucose‐induced insulin secretion in the offspring and changed the plasma lipid profile among offspring of different groups.
Maternal dietary vitamin restriction increases body fat content but not insulin resistance in WNIN rat offspring up to 6 months of age
TLDR
It is hypothesised that chronic maternal vitamin restriction predisposes the offspring to insulin resistance syndrome in later life through changes in adiposity and fat metabolism.
Maternal nutrient restriction affects properties of skeletal muscle in offspring
TLDR
It is demonstrated that the early to mid‐gestation period is important for skeletal muscle development, as impaired muscle development during this stage of gestation affects the number and composition of fibres in offspring which may lead to long‐term physiological consequences, including predisposition to obesity and diabetes.
Effects of birth weight and postnatal nutrition on neonatal sheep: II. Skeletal muscle growth and development.
TLDR
It is suggested that myofiber number in fetal sheep muscles is established before the presumed, negative effects of inadequate fetal nutrient supply on skeletal muscle growth and development become apparent.
Beta-cell mass and proliferation following late fetal and early postnatal malnutrition in the rat
TLDR
Subsequent re-nutrition is followed by increased beta-cell proliferation but this is insufficient to fully restore Beta-cell mass, as shown in rats born and nursed by food-restricted mothers.
The effect of maternal undernutrition before muscle differentiation on the muscle fiber development of the newborn lamb.
TLDR
It has been shown that decreased maternal diet before muscle fiber formation will alter the muscle fiber development in the fetus and change the muscle characteristics of the newborn lambs.
Cellular Development of Skeletal Muscle during Early Periods of Nutritional Restriction and Subsequent Rehabilitation
TLDR
The ability of muscles to recover from a nutritional restriction appears to directly relate to the ability to achieve a normal complement of muscle nuclei (DNA).
...
1
2
3
4
5
...