Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, CB1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion.

@article{LpezGallardo2012MaternalDA,
  title={Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, CB1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion.},
  author={Meritxell L{\'o}pez-Gallardo and Ana Bel{\'e}n L{\'o}pez-Rodr{\'i}guez and {\'A}lvaro Llorente-Berzal and David Rotllant and Ken Mackie and Antonio Armario and Roser Nadal and M Viveros},
  journal={Neuroscience},
  year={2012},
  volume={204},
  pages={90-103}
}
We have recently reported that early maternal deprivation (MD) for 24 h [postnatal day (PND) 9-10] and/or an adolescent chronic treatment with the cannabinoid agonist CP-55,940 (CP) [0.4 mg/kg, PND 28-42] in Wistar rats induced, in adulthood, diverse sex-dependent long-term behavioral and physiological modifications. Here we show the results obtained from… CONTINUE READING