Maternal control of vertebrate dorsoventral axis formation and epiboly by the POU domain protein Spg/Pou2/Oct4.

@article{Reim2006MaternalCO,
  title={Maternal control of vertebrate dorsoventral axis formation and epiboly by the POU domain protein Spg/Pou2/Oct4.},
  author={Gerlinde Reim and M. P. Molina Brand},
  journal={Development},
  year={2006},
  volume={133 14},
  pages={
          2757-70
        }
}
Dorsoventral (DV) axis formation of the vertebrate embryo is controlled by the maternal genome and is subsequently refined zygotically. In the zygote, repression of ventralizing Bmp activity on the dorsal side through chordin and noggin is crucial for establishment of a dorsally located organizer. This interplay generates a zygotic Bmp activity gradient that defines distinct positional values along the DV axis. The maternal processes that control expression of the zygotic genes implicated in DV… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 49 CITATIONS

Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development

  • Molecular systems biology
  • 2010
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Zygotic Genome Activators, Developmental Timing, and Pluripotency.

  • Current topics in developmental biology
  • 2016
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 90 REFERENCES

Maternal induction of ventral fate by zebrafish radar.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2003
VIEW 19 EXCERPTS
HIGHLY INFLUENTIAL

Dorsoventral patterning in the zebrafish: bone morphogenetic proteins and beyond.

  • Results and problems in cell differentiation
  • 2002
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Axis formation and patterning in zebrafish.

  • Current opinion in genetics & development
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Oct-4: control of totipotency and germline determination.

  • Molecular reproduction and development
  • 2000
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

mRNA localization patterns in zebrafish oocytes

  • Mechanisms of Development
  • 2000
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

The zebrafish epiboly mutants.

VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL