Maternal care influences neuronal survival in the hippocampus of the rat.

@article{Bredy2003MaternalCI,
  title={Maternal care influences neuronal survival in the hippocampus of the rat.},
  author={Timothy W Bredy and Rebecca J. Grant and Danielle L. Champagne and Michael J. Meaney},
  journal={The European journal of neuroscience},
  year={2003},
  volume={18 10},
  pages={2903-9}
}
Maternal care during the first week of postnatal life influences hippocampal development and function (Liu et al., 2000; Nature Neurosci., 3, 799-806). Offspring reared by mothers who exhibit increased levels of pup licking/grooming (LG) show increased hippocampal synaptic density and enhanced spatial learning and memory. Using 5-bromo-2'-deoxyuridine (BrdU), a thymidine analogue incorporated into cells during DNA synthesis, we examined the effects of early maternal care on hippocampal cell… CONTINUE READING

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