Maternal caffeine exposure impairs insulin secretion by pancreatic β-cells and increases the risk of type II diabetes mellitus in offspring.

@article{Sun2014MaternalCE,
  title={Maternal caffeine exposure impairs insulin secretion by pancreatic β-cells and increases the risk of type II diabetes mellitus in offspring.},
  author={Tingting Sun and Jinghui Guo and Hui Chen and Jieting Zhang and Xiaohu Zhang and Xiaohua Jiang and Fuqiang Wang and Zhiyang Xu and Xiaoyan Huang and Jiahao Sha and Hsiao Chang Chan},
  journal={Cell biology international},
  year={2014},
  volume={38 10},
  pages={
          1183-93
        }
}
Maternal caffeine exposure may be one of the causes for intrauterine growth retardation and low birth weight (LBW), and increased risk of type 2 diabetes mellitus (T2DM) in the adulthood has been associated with LBW. However, whether maternal caffeine exposure contributes to T2DM development of her offspring has not been fully investigated. We have investigated the influence of maternal caffeine exposure on glucose homeostasis in vivo and effects of long-term caffeine load on insulin secretion… CONTINUE READING
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