Maternal autoantibody profiles at risk for autoimmune congenital heart block: a prospective study in high-risk patients.

@article{Tonello2016MaternalAP,
  title={Maternal autoantibody profiles at risk for autoimmune congenital heart block: a prospective study in high-risk patients.},
  author={M Tonello and Amelia Ruffatti and Maria Favaro and Tiziana Tison and Teresa del Ross and Antonia Calligaro and Ariela Hoxha and Elena Mattia and Leonardo Punzi},
  journal={Lupus science & medicine},
  year={2016},
  volume={3 1},
  pages={e000129}
}
OBJECTIVE This prospective study aimed to identify antibody profiles characterising mothers with fetuses developing congenital heart block (CHB) by comparing their antibody frequencies and levels with those in unaffected mothers. METHODS Eighty-one consecutive pregnant patients positive to anti-Ro±anti-La antibodies, at high risk of developing fetal CHB were prospectively studied. The 16 patients with fetal CHB outcome were considered the study population and the 65 patients with normal… CONTINUE READING
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