Maternal and sibling microchimerism in twins and triplets discordant for neonatal lupus syndrome-congenital heart block.

@article{Stevens2005MaternalAS,
  title={Maternal and sibling microchimerism in twins and triplets discordant for neonatal lupus syndrome-congenital heart block.},
  author={Albert M. Stevens and Hubertus Franciscus Maria Hermes and Nathalie C. Lambert and Jessica Lee Nelson and Pier Luigi Meroni and Roland Cimaz},
  journal={Rheumatology},
  year={2005},
  volume={44 2},
  pages={
          187-91
        }
}
OBJECTIVE Neonatal lupus syndrome-congenital heart block (NLS-CHB) is an acquired autoimmune disease in which maternal autoantibodies are necessary but not sufficient for disease. Maternal myocardial cells have been found in the hearts of patients with NLS-CHB, suggesting that maternal microchimerism may also play a role. In this study we asked whether levels of microchimerism in the blood are associated with NLS-CHB in discordant twins and triplets. METHODS Human leucocyte antigen (HLA… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 28 REFERENCES

: fetal myocarditis progressing to atrioventricular block in triplets

  • JL Nelson, DE Furst, S Maloney
  • 2003

Similar Papers

Loading similar papers…