• DOI:10.1002/(SICI)1520-6866(1999)19:6<369::AID-TCM1>3.0.CO;2-R
Corpus ID: 43674324

Maternal and fetal toxicity of N-methylmorpholine by oral administration in rats.

@article{Sitarek1999MaternalAF,
  title={Maternal and fetal toxicity of N-methylmorpholine by oral administration in rats.},
  author={K. Sitarek},
  journal={Teratogenesis, carcinogenesis, and mutagenesis},
  year={1999},
  volume={19 6},
  pages={
          369-76
        }
}

• K. Sitarek
• Published 1999
• Biology, Medicine
• Teratogenesis, carcinogenesis, and mutagenesis

N-methylmorpholine, which is used as a catalyst in polyurethane foams producing, in solvents, stabilizing agents, and corrosion inhibitors, was administered to female rats by gavage at 100, 200, 600, and 900 mg/kg during organogenesis. It did not exhibit selective toxicity toward the developing conceptus. This compound administered to pregnant females was fetotoxic and teratogenic in the presence of maternal toxicity. N-methylmorpholine induced anophthalmia, internal hydrocephalus, and… Expand

View on PubMed

doi.org

Save to Library

Create Alert

Cite

Launch Research Feed