Maternal age and ovarian stimulation independently affect oocyte mtDNA copy number and cumulus cell gene expression in bovine clones.

Abstract

STUDY QUESTION Does maternal ageing and ovarian stimulation alter mitochondrial DNA (mtDNA) copy number and gene expression of oocytes and cumulus cells from a novel bovine model for human IVF? SUMMARY ANSWER Oocytes collected from females with identical nuclear genetics show decreased mtDNA copy number and increased expression of an endoplasmic reticulum… (More)
DOI: 10.1093/humrep/dev066

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@article{Cree2015MaternalAA, title={Maternal age and ovarian stimulation independently affect oocyte mtDNA copy number and cumulus cell gene expression in bovine clones.}, author={Lynsey M. Cree and Elizabeth R Andersen Hammond and Andrew N Shelling and Martin C. Berg and John C. Peek and Mark P. Green}, journal={Human reproduction}, year={2015}, volume={30 6}, pages={1410-20} }