Maternal Origins of Developmental Reproducibility

@article{Petkova2014MaternalOO,
  title={Maternal Origins of Developmental Reproducibility},
  author={Mariela D. Petkova and Shawn C. Little and Feng Liu and Thomas Gregor},
  journal={Current Biology},
  year={2014},
  volume={24},
  pages={1283-1288}
}
Cell fate decisions during multicellular development are precisely coordinated, leading to highly reproducible macroscopic structural outcomes [1-3]. The origins of this reproducibility are found at the molecular level during the earliest stages of development when patterns of morphogen molecules emerge reproducibly [4, 5]. However, although the initial conditions for these early stages are determined by the female during oogenesis, it is unknown whether reproducibility is perpetuated from… CONTINUE READING
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