Maternal Nicotine Induces Collagen Type IV Changes in the Mice Lung Parenchyma and its Vessels

@inproceedings{Mohammadi2011MaternalNI,
  title={Maternal Nicotine Induces Collagen Type IV Changes in the Mice Lung Parenchyma and its Vessels},
  author={Shabnam Mohammadi and Mohammad Reza Nikravesh and Mehdi Jalali and Abbas Ali Moeen and Mohammad Hassan Karimfar},
  booktitle={Tanaffos},
  year={2011}
}
BACKGROUND One of the undesirable effects of maternal nicotine exposure during pregnancy is pulmonary hypertension. Since nicotine binds to its receptors on pulmonary vessels the hypothesis of this research was the possible structural changes that nicotine may cause on newborn vessels. MATERIALS AND METHODS Twenty-four female BALB/c mice were mated and finding vaginal plug was assumed as day zero of pregnancy. Pregnant mice were divided into 2 experimental and 2 control groups. Experimental… CONTINUE READING