Maternal Manganese Restriction Increases Susceptibility to High-Fat Diet-Induced Dyslipidemia and Altered Adipose Function in WNIN Male Rat Offspring

  title={Maternal Manganese Restriction Increases Susceptibility to High-Fat Diet-Induced Dyslipidemia and Altered Adipose Function in WNIN Male Rat Offspring},
  author={Manisha Ganeshan and Pothaganti B. Sainath and Inagadapa J.N. Padmavathi and Lagishetty Venu and Yedla Durga Kishore and Kalle Anand Kumar and Nemani Harishanker and J. Srinivasa Rao and Manchala Raghunath},
  journal={Experimental Diabetes Research},
Growth in utero is largely a reflection of nutrient and oxygen supply to the foetus. We studied the effects of Mn restriction per se, maternal Mn restriction, and postnatal high-fat feeding in modulating body composition, lipid metabolism and adipocyte function in Wistar/NIN (WNIN) rat offspring. Female weanling, WNIN rats received ad libitum for 4 months, a control or Mn-restricted diet and were mated with control males. Some restricted mothers were rehabilitated with control diet from… 

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