Maternal Diabetes, Large-for-Gestational-Age Births, and First Trimester Pregnancy-Associated Plasma Protein-A.

@article{Wells2015MaternalDL,
  title={Maternal Diabetes, Large-for-Gestational-Age Births, and First Trimester Pregnancy-Associated Plasma Protein-A.},
  author={George Anthony Wells and Kerrin Bleicher and Xuguang Han and Monika McShane and Yuk Fun Chan and Amanda Bartlett and Chris P. White and Sue Mei Lau},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2015},
  volume={100 6},
  pages={
          2372-9
        }
}
CONTEXT Maternal pregnancy-associated plasma protein-A (PAPP-A) is measured at nuchal translucency scanning to assess the risk of fetal chromosomal disorders. OBJECTIVE The aim of this study was to examine whether PAPP-A might also be a predictor of gestational diabetes (GDM), type 2 diabetes (T2D), or large-for-gestational-age (LGA) births. DESIGN PAPP-A levels were measured in serum from 1664 women at their 10-14-week nuchal translucency scan at a tertiary referral hospital. Maternal… CONTINUE READING

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Pregnancy-associated plasma protein-A is positively correlated with first-trimester skin microvascular reactivity.

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