Maternal Clofibrate Administration Amplifies Fetal Peroxisomes


ABSTRACT: To study the effects of peroxisome proliferators on fetal biogenesis, 400 mg/kg oral clofibrate was administered to pregnant mice beginning at d 6 of gestation. Maternal/fetal tissues from three separate experiments were harvested between gestational d 13 and 19 and maternal/fetal tissues were assayed for peroxisomal matrix, membrane-associated… (More)
DOI: 10.1203/00006450-199103000-00007


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