Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan

@inproceedings{Piper2017MatchingDA,
  title={Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan},
  author={Matthew W D Piper and George A. Soultoukis and Eric Blanc and Andrea Mesaros and Samantha L. Herbert and Paula Juricic and Xiaoli He and Ilian Atanassov and Hanna Salmonowicz and Mingyao Yang and Stephen J. Simpson and Carlos Ribeiro and Linda Partridge},
  booktitle={Cell metabolism},
  year={2017}
}
Balancing the quantity and quality of dietary protein relative to other nutrients is a key determinant of evolutionary fitness. A theoretical framework for defining a balanced diet would both reduce the enormous workload to optimize diets empirically and represent a breakthrough toward tailoring diets to the needs of consumers. Here, we report a simple and powerful in silico technique that uses the genome information of an organism to define its dietary amino acid requirements. We show for the… CONTINUE READING
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