Masugi nephritis produced by the antiserum to heterologous glomerular basement membrane. I. Results in mice.

@article{Nishihara1981MasugiNP,
  title={Masugi nephritis produced by the antiserum to heterologous glomerular basement membrane. I. Results in mice.},
  author={Tatsuji Nishihara and Yoji Kusuyama and Eq Gen and Naofumi Tamaki and Kensuke Saito},
  journal={Acta pathologica japonica},
  year={1981},
  volume={31 1},
  pages={85-92}
}
Nephrotoxic activity of rabbit antisera to glomerular basement membrane (GBM) from three different donors (rat, gerbil, and man) was examined in mice of various strains. Animals receiving a small dose (0.1 ml) of anti-rat GBM or a large dose (0.3 ml X 2) of anti-gerbil GBM developed massive proteinuria and irreversible glomerular lesions which were… CONTINUE READING