Mastoparan, a peptide toxin from wasp venom, stimulates glycogenolysis mediated by an increase of the cytosolic free Ca2+ concentration but not by an increase of cAMP in rat hepatocytes.

@article{Tohkin1990MastoparanAP,
  title={Mastoparan, a peptide toxin from wasp venom, stimulates glycogenolysis mediated by an increase of the cytosolic free Ca2+ concentration but not by an increase of cAMP in rat hepatocytes.},
  author={M Tohkin and Tatsurou Yagami and Toshiyuki Matsubara},
  journal={FEBS letters},
  year={1990},
  volume={260 2},
  pages={179-82}
}
A wasp venom, mastoparan, rapidly increased the cytosolic free Ca2+ concentration [( Ca2+]i) and activated phosphorylase in rat hepatocytes in a concentration-dependent manner. Mastoparan could increase [Ca2+]i even in the absence of extracellular Ca2+, but a larger increase was observed in the presence of extracellular Ca2+. Thus, mastoparan mobilized Ca2… CONTINUE READING