• Corpus ID: 53497210

Mastic liposome treatment for shiny and impure skin

@inproceedings{Wandrey2015MasticLT,
  title={Mastic liposome treatment for shiny and impure skin},
  author={Franziska Wandrey and Daniel Schmid},
  year={2015}
}

• F. Wandrey, D. Schmid
• Published 2015
• Chemistry

Mastic is the resin harvested from the Pistacia lentiscus trees from the Greek island of Chios. It has been used as a precious natural remedy against various ailments since ancient times. The water-insoluble oleoresin was made available for skin care application by stabilising it in a liposomal preparation. In this form, mastic inhibits the sebum production enhancing enzyme 5a-reductase type I in vitro. In clinical studies with volunteers suffering from oily skin and impurities it was shown that mastic visibly reduces pore size, shininess and the number of blemishes, which makes mastic an ideal active to treat impure skin. Figure 1: Dried mastic resin. Figure 2: Inhibition of 5a-reductase type I activity by mastic liposomes and determination of the IC50 value. Figure 3: Pore refinement after treatment with placebo cream or a cream containing 2% mastic liposomes. Concentration (mg/mL) After 14 days After 28 days 5 a re du ct as e I in hi bi ti on ( % ) Po re r ef in em en t co m pa ri so n (% ) 100