Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8–Akt–Slug pathway

Abstract

There is increasing evidence that mast cells (MCs) and their mediators are involved in the remodeling of the tumor microenvironment and promote tumor growth, angiogenesis and metastasis. We have found that an increased density of MCs in thyroid cancer (TC) correlates with enhanced invasiveness. However, the MC-derived factors responsible for this activity… (More)
DOI: 10.1038/onc.2014.441

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@article{Visciano2015MastCI, title={Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8–Akt–Slug pathway}, author={Carla Visciano and Federica Liotti and Nella Prevete and Gaetano Cali' and Ramon A Franco and Francesca Collina and Amato de Paulis and Gianni Marone and Massimo M Santoro and Rosa Marina Melillo}, journal={Oncogene}, year={2015}, volume={34}, pages={5175-5186} }