Mast cells in systemic mastocytosis have distinctly brighter CD45 expression by flow cytometry.

@article{Chisholm2015MastCI,
  title={Mast cells in systemic mastocytosis have distinctly brighter CD45 expression by flow cytometry.},
  author={Karen M. Chisholm and Jason Merker and Jason R. Gotlib and Gary M Gitana and Martina I. Lefterova and James L Zehnder and Tracy I George and Daniel Alan Arber and Robert S Ohgami},
  journal={American journal of clinical pathology},
  year={2015},
  volume={143 4},
  pages={527-34}
}
OBJECTIVES We sought to determine the significance of bright CD45 expression on mast cells in cases of systemic mastocytosis vs mast cells in bone marrows uninvolved by systemic mastocytosis and compare this CD45 expression with CD25 and CD2 expression on mast cells. METHODS Multiparameter flow cytometry was performed on 31 cases of systemic mastocytosis… CONTINUE READING