Mast cells in human adipose tissue: link with morbid obesity, inflammatory status, and diabetes.

@article{Divoux2012MastCI,
  title={Mast cells in human adipose tissue: link with morbid obesity, inflammatory status, and diabetes.},
  author={Adeline Divoux and Sandrine Moutel and Christine Poitou and Dani{\`e}le Lacasa and Nicolas Veyrie and Abdelhalim Aissat and Michel Arock and Mich{\'e}le Guerre-Millo and Karine Cl{\'e}ment},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2012},
  volume={97 9},
  pages={E1677-85}
}
AIMS AND HYPOTHESIS Mast cells are immune cells known for their role in several inflammatory and fibrotic diseases. Recent works in mice suggest that mast cells could be cellular actors involved in the pathophysiology of obesity, a disease characterized by white adipose tissue (WAT) and systemic inflammation. The aim of the study was to better characterize mast cells in WAT of obese with or without type 2 diabetes and lean subjects as well as to explore the relationship with WAT inflammation… CONTINUE READING
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