Mast cells contribute to the stromal microenvironment in mammary gland branching morphogenesis.

@article{Lilla2010MastCC,
  title={Mast cells contribute to the stromal microenvironment in mammary gland branching morphogenesis.},
  author={Jennifer N Lilla and Zena Werb},
  journal={Developmental biology},
  year={2010},
  volume={337 1},
  pages={124-33}
}
The stromal microenvironment regulates mammary gland branching morphogenesis. We have observed that mast cells are present in the mammary gland throughout its postnatal development and, in particular, are found around the terminal end buds and ductal epithelium of the pubertal gland. Mast cells contribute to allergy, inflammatory diseases, and cancer development but have not been implicated in normal development. Genetic and pharmacological disruption of mast cell function in the mammary gland… CONTINUE READING
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