Mast cells are required in the proliferation and remodeling phases of microdeformational wound therapy.

@article{Younan2011MastCA,
  title={Mast cells are required in the proliferation and remodeling phases of microdeformational wound therapy.},
  author={George J Younan and Yvonne I Heit and Pouya Dastouri and Hussein Kekhia and Wei Xing and Michael F. Gurish and Dennis Paul Orgill},
  journal={Plastic and reconstructive surgery},
  year={2011},
  volume={128 6},
  pages={649e-58e}
}
BACKGROUND Mast cells are important in numerous inflammatory processes. They are also mechanosensitive and likely play an important role in wound healing. The authors hypothesized that mechanical alteration of the wound environment with a distributed suction device could link mast cells to the healing cascade. METHODS Controlled uniform full-thickness wound surface microdeformations were induced by suction combined with an open-pore polyurethane foam (microdeformational wound therapy) in mast… CONTINUE READING