Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma.

@article{Qu1995MastCA,
  title={Mast cells are a major source of basic fibroblast growth factor in chronic inflammation and cutaneous hemangioma.},
  author={Z Qu and Janice M Liebler and Michael R Powers and T Galey and Peyman Ahmadi and Xueyin N. Huang and John C. Ansel and Joseph Butterfield and Stephen R. Planck and James T. Rosenbaum},
  journal={The American journal of pathology},
  year={1995},
  volume={147 3},
  pages={564-73}
}
Mast cells play an essential role during development of inflammation after chemical and immunological insults and have been implicated in tissue fibrosis and angiogenesis. The exact contribution of mast cells to these conditions is largely unknown. In this study, we found that a potent angiogenic and mitogenic polypeptide, basic fibroblast growth factor (bFGF), is localized to the majority of mast cells from normal skin and lung and in tissue samples characterized by fibrosis, hyperplasia, and… CONTINUE READING
94 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 94 extracted citations

Similar Papers

Loading similar papers…