Mast cells and their activation in lung disease.

@article{Virk2016MastCA,
  title={Mast cells and their activation in lung disease.},
  author={Harvinder Virk and Greer Arthur and Peter Bradding},
  journal={Translational research : the journal of laboratory and clinical medicine},
  year={2016},
  volume={174},
  pages={
          60-76
        }
}
Mast cells and their activation contribute to lung health via innate and adaptive immune responses to respiratory pathogens. They are also involved in the normal response to tissue injury. However, mast cells are involved in disease processes characterized by inflammation and remodeling of tissue structure. In these diseases mast cells are often inappropriately and chronically activated. There is evidence for activation of mast cells contributing to the pathophysiology of asthma, pulmonary… CONTINUE READING
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