Mast cells and macrophages exert beneficial and detrimental effects on tumor progression and angiogenesis.

@article{Ribatti2013MastCA,
  title={Mast cells and macrophages exert beneficial and detrimental effects on tumor progression and angiogenesis.},
  author={Domenico Ribatti},
  journal={Immunology letters},
  year={2013},
  volume={152 2},
  pages={83-8}
}
Mast cells and macrophages are critical regulators of inflammation and immunological response in the tumor microenvironment. Increased number of mast cells and macrophages have been reported to correlate with poor prognosis in numerous solid and hematological tumors. In contrast to their pro-tumorigenic role, mast cells and macrophages have shown also anti-tumorigenic effect in certain malignancies, for example by supporting cancer rejection. Thus, mast cells and macrophages can exert both… CONTINUE READING
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