Mast cells: multifaceted immune cells with diverse roles in health and disease.

@article{Rao2008MastCM,
  title={Mast cells: multifaceted immune cells with diverse roles in health and disease.},
  author={K Narasimha Rao and Melissa A Brown},
  journal={Annals of the New York Academy of Sciences},
  year={2008},
  volume={1143},
  pages={83-104}
}
Mast cells were discovered more than 100 years ago and until recently, have been considered renegades of the host with the sole purpose of perpetuating allergy. The discovery of mast cell-deficient mice that could be reconstituted with mast cells (the so called "mast cell knock-in" mice) has allowed the study of the in vivo functions of mast cells and revealed several new facets of these cells. It is now evident that mast cells have a much broader impact on many physiological and pathologic… CONTINUE READING

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