Mast cell-tumor cell interactions: for or against tumour growth and metastasis?

  title={Mast cell-tumor cell interactions: for or against tumour growth and metastasis?},
  author={Violetta Dimitriadou and Michael Koutsilieris},
  journal={Anticancer research},
  volume={17 3A},
This review comes up with the possible association between mast cells and tumour progression and summarizes some of the most recent data on the subject. The accumulation of mast cells around tumour areas is a very old observation. However, the functional significance of such phenomenon is a subject of controversy because of contradictory experimental data. In this review, two hypotheses are suggested. The first, refers on the possibility that the accumulation of mast cells is part of a general… CONTINUE READING

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