Mast cell involvement in interstitial cystitis.

  title={Mast cell involvement in interstitial cystitis.},
  author={W L Lynes and Stuart D. Flynn and Linda M. Dairiki Shortliffe and Michael J Lemmers and Robert D. Zipser and L. Jackson Roberts and Thomas A. Stamey},
  journal={The Journal of urology},
  volume={138 4},
A prospective study was designed to examine the relationship of mast cells, and eosinophilic leukocyte density and mediator levels to clinical and histological parameters of interstitial cystitis. Interstitial cystitis and control patients underwent bladder biopsy with histological examination, and quantification of intact and degranulated mast cell and eosinophilic leukocyte density. In addition, bladder tissue histamine content, urinary prostaglandin E2 excretion rates, and serum and urinary… CONTINUE READING