Mast cell interactions with the nervous system: relationship to mechanisms of disease.

@article{Dines1997MastCI,
  title={Mast cell interactions with the nervous system: relationship to mechanisms of disease.},
  author={Karla Dines and Henry C. Powell},
  journal={Journal of neuropathology and experimental neurology},
  year={1997},
  volume={56 6},
  pages={627-40}
}
In summary, mast cell interactions in the nervous system are relevant to both physiological processes (i.e. reproduction) and pathologic states (i.e. inflammatory demyelination, painful disorders, toxic and metabolic disease, and tumor angiogenesis). Their physiologic roles may contribute to gender-related vulnerability to inflammatory disease and may modulate sensitivity to pain. Mast cells are universally involved in tissue repair and they release and respond to trophic factors such as NGF… CONTINUE READING

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