Mast cell glycosaminoglycans

@inproceedings{Mulloy2016MastCG,
  title={Mast cell glycosaminoglycans},
  author={Barbara Mulloy and R. F. Lever and Clive P Page},
  booktitle={Glycoconjugate Journal},
  year={2016}
}
Mast cells contain granules packed with a mixture of proteins that are released on degranulation. The proteoglycan serglycin carries an array of glycosaminoglycan (GAG) side chains, sometimes heparin, sometimes chondroitin or dermatan sulphate. Tight packing of granule proteins is dependent on the presence of serglycin carrying these GAGs. The GAGs of mast cells were most intensively studied in the 1970s and 1980s, and though something is known about the fine structure of chondroitin sulphate… CONTINUE READING
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