Mast cell-derived cytokine expression induced via Fc receptors and Toll-like receptors.

@article{Okayama2005MastCC,
  title={Mast cell-derived cytokine expression induced via Fc receptors and Toll-like receptors.},
  author={Yoshimichi Okayama},
  journal={Chemical immunology and allergy},
  year={2005},
  volume={87},
  pages={101-10}
}
It is now well established that human mast cells (MCs) are a source of several multifunctional cytokines. Preformed immunoreactive tumor necrosis factor-alpha (TNF-alpha) has been observed within human skin, and pulmonary MC granules are released after IgE-dependent activation. Recent studies in animal models indicate that mouse MCs may play a protective role in host defense against bacteria through production of TNF-alpha, mainly as a result of Toll-like receptor 4 (TLR4)- or CD48-mediated… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…